Black women who drink more than 14 alcoholic drinks per week have a significantly higher risk of invasive breast cancer than those who drink less, a new study suggests.
The findings confirmed the link between alcohol consumption and breast cancer risk, which has been seen in other studies drawn from majority white populations.
And while some breast cancer risk factors—like age or genetics—aren’t easily modified, alcohol consumption is one risk factor that women can change to potentially lower their cancer risk.
“…women who are concerned about their risk of breast cancer could consider reducing levels of exposure…”
“Minority groups are often understudied because they represent a smaller proportion of study populations. This work avoided that limitation by working with a consortium of many different studies, including more than 20,000 black women,” says Melissa Troester, a member of the University of North Carolina Lineberger Comprehensive Cancer Center and professor of epidemiology in the university’s Gillings School of Global Public Health.
“We found that the patterns observed in other studies examining alcohol and breast cancer risk hold in black women, too.”
The researchers analyzed data for 22,338 women from the African American Breast Cancer Epidemiology and Risk (AMBER) consortium, which combines data from four large breast cancer studies. Researchers evaluated alcohol as a risk factor for invasive breast cancer as well as for specific breast cancer subtypes, such as estrogen receptor positive or negative cancer.
“Our study demonstrated there is benefit in creating consortia to focus on understudied groups,” says first author Lindsay Williams, a graduate research assistant.
When they studied the data across all breast cancer subtypes, they found consuming seven or more alcoholic drinks per week was linked to increased risk of breast cancer across all subtypes. Women who previously drank alcohol, and later stopped, had lower risk than women who reported recent use—indicating that women may be able to reduce their risk by drinking less.
However, they did find significantly higher risk for some women who have never drank alcohol. The researchers say that the group of women that avoids alcohol also sometimes includes women who have other health conditions, and some of these health conditions can increase risk for breast cancer. The finding may direct additional research.
“In the future, it may be worth-while to better characterize women who identify as never drinkers to understand reasons for abstaining from alcohol,” Williams says.
The researchers underscore that the study is important as alcohol consumption can be changed or addressed.
“Overall, our findings among African American women mirror those reported in the literature for white women, namely that high levels of alcohol intake—more than one drink per day—are associated with increased breast cancer risk,” Troester says.
“Alcohol is an important modifiable exposure, and women who are concerned about their risk of breast cancer could consider reducing levels of exposure,” she adds.
The study appears in the journal Cancer, Epidemiology, Biomarkers & Prevention. The National Institutes of Health, the Komen for the Cure Foundation, the Breast Cancer Research Foundation, and the University Cancer Research Fund supported the work.
Source: UNC-Chapel Hill
Alcohol Consumption and Cancer Risk: Understanding Possible Causal Mechanisms for Breast and Colorectal Cancers: Evidence Report/Technology Assessment Number 197
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