Mighty Natural

The Best Option For Cancer Fatigue Isn’t A Pill

The Best Option For Cancer Fatigue Isn’t A PillExercise and/or psychological therapy work better than medications to reduce cancer-related fatigue and should be recommended first to patients, say researchers.

Why The Disability Risk Rises After Older Adults Visit ER

The Disability Risk Rises After Older Adults Visit EROlder adults who go to the emergency department for an illness or injury are at increased risk for disability and decline in physical abilities up to six months later, research shows.

Could A Bored Brain Predict Teen Drug Abuse?

bored teenager 02 26There’s no easy way to predict which teenager will become a problem drug user. While certain personality traits—impulsiveness for example—may signal danger, not every adolescent fits the description.

How Chronic Stress Could Be Making You Fat

How Chronic Stress Could Be Making You FatThe world is getting fatter and it’s making us sicker. But could rising stress levels be playing an important role in our growing waistlines?

Video Games Can Help Children With Cerebral Palsy

Video Games Can Help Children With Cerebral PalsyCerebral palsy (CP) is the most common childhood physical disability, affecting more than 17 million people worldwide. The condition results when there is an injury to the developing brain that goes on to affect a child’s movement and posture...

Diabetes Could Be Causing Up To 12% Of All US Deaths

Diabetes Could Be Causing Up To 12% Of All US DeathsThe proportion of deaths attributable to diabetes in the US is as high as 12 percent—three times higher than estimates based on death certificates suggest—a new analysis shows.

Which Approach Is Best For Preventing Heart Disease?

Which Approach Is Best For Preventing Heart Disease?Cardiovascular disease is the number one killer worldwide and the second biggest killer in the UK. However, most cases of heart disease can be prevented by managing risk factors.

Do Emotions Play A Role in Cancer Resistance and Cancer Survival?

Do Emotions Play A Role in Cancer Resistance and Cancer Survival?Under emotional distress, the brain may signal the adrenal glands to produce chemicals called corticosteroids. Cancer-related processes are accelerated in the presence of these chemicals. Certain cancers have also been associated with distressing life events.

Here's What Actually Does Work For Back Pain

Here's What Actually Does Work For Back PainHow’s your back? About a quarter of Australia’s population experience a back pain episode at any point in time, and nearly all of us (around 85%) will have at least one lifetime experience with back pain.

Why We Lose Our Hearing And Vision As We Age

Why We Lose Our Hearing And Vision As We Age

As the baby boomer generation begins to age, the prevalence of both eye and ear disease will rise exponentially, as there is a strong correlation between vision loss, hearing loss and ageing.

The Battle Between Who We Are and Who We Want to Be

Who Is In Charge? You or Chocolate?Many of us do things we wish we would not do. We may compulsively eat sugary or fatty things, drink too much alcohol, become a zombie in front of the TV, or whatever. We may judge ourselves as “weak” or “lacking in willpower”, because of this. Maybe we...

How Is It Possible To Just Think Pain Away?

How It's Possible To Just Think Pain AwayPleasure and pain are always coming and going, fluctu­ating to and fro, sometimes only five minutes apart, doing “their thing” to this flesh-and-bone vehicle, inspiring all kinds of crazy thoughts in our thinking organ—the brain.

5 Common Myths About The Aging Brain And Body

5 Common Myths About The Aging Brain And BodyThe world’s population is ageing. The number of adults aged 65 and over is increasing, as is the proportion of the population they represent. However, there are a number of myths associated with what happens to our brain and bodies as we age.

Can Burnt Food Give You Cancer?

Can Burnt Food Give You Cancer?If you’re offered a plate of blackened barbecue food this summer, you might think twice about eating it. It’s commonly thought that food that has been burnt could cause cancer.

How Do You Know If You're Obsessed With Your Health?

How Do You Know If You're Obsessed With Your Health?Most of us worry about our health at some point. You may notice a new symptom or change in your body and become convinced it’s a sign of a horrible illness; a loved one might become ill and you might worry it may also happen to you.

Can Marijuana Treat MS Symptoms?

Can Marijuana Treat MS Symptoms? An estimated 400,000 Americans are currently living with multiple sclerosis, an autoimmune disease where the body’s immune cells attack a fatty substance called myelin in the nerves.

Why Heart Failure Is Not As Common A Death As Reports Imply

Why Heart Failure Is Not As Common A Death As Reports ImplyWhen George Michael died last year news reports all over the world announced the cause as heart failure. While they are all related to each other, “heart failure”, “heart attack” and “sudden cardiac arrest” are not synonyms.

Is Snoring Anything To Worry About?

Snorers may be banished from the bedroom, disrupting intimate relationships. restlessglobetrotter/flickr, CC BYThere’s nothing quite like the sound of snoring as the ultimate sleep interrupter.

Anxiety Can Lead Men To Overtreat Prostate Cancer

Anxiety Can Lead Men To Overtreat Prostate CancerThe anxiety many men experience after being diagnosed with prostate cancer may lead them to choose potentially unnecessary treatment options, researchers report.

Why Heart Attacks Are More Common In January

Why Heart Attacks Are More Common In JanuaryCardiovascular deaths around the world, such as heart attacks and strokes, peak in January. Why this is the case has baffled scientists for some time, but new evidence is starting to unravel the mystery.

Why The Kidneys Play A Vital Role In Health And Longevity

Why The Kidneys Play A Vital Role In Health And LongevityTo make the most of your energy, look to nature as your guide. For example, for a plant to survive long term, it requires strong roots–ones that pull in nutrients and water from its environment and give it the strength to carry on.

This Single Brain Activity Might Diagnose A Concussion

This Single Brain Activity Might Diagnose A ConcussionCurrently there is not a single test that can reliably and objectively diagnose concussions, but new research suggests measuring the brain’s response to sound could take the guesswork out of the diagnosis.

Five Little-known Diseases That Might Emerge In 2017

Five Little-known Diseases That Might Emerge In 2017The phrase “emerging disease”, to describe an infectious disease that is new to humans or which is suddenly increasing its geographical range or number of cases, dates back to the 1960s.

How The Brain Helps The Body Fight Bacteria

How The Brain Helps The Body Fight BacteriaThe brain may not only control our thoughts and basic physical functions. Recent studies indicate that it also controls the way our body responds to the threat of bacterial infections.

Does Your Brain Really Freeze When You Eat Ice Cream Too Fast?

Does Your Brain Really Freeze When You Eat Ice Cream Too Fast?It’s a long, hot summer’s day and you’re looking forward to an ice cream. But within seconds of your first bite, you feel a headache coming on: a brain freeze. What’s going on?

Health Risks Associated with Early Puberty for Girls

Why Some Girls Grow Breasts Too Early When a girl’s breasts start growing early, it can be a sign she will develop certain diseases later in life. There is evidence of early puberty leading to increased risk of obesity, type 2 diabetes, heart disease and cancer – particularly breast cancer.

Nausea From Pregnancy Can Be Life Threatening

Can Nausea From Pregnancy Be Life Threatening?Most women experience some type of morning sickness during pregnancy, but some women develop a far more serious condition, hyperemesis gravidarum.

A Brain Implant That Lets Paralyzed Monkeys Walk

 A Brain Implant That Lets Paralyzed Monkeys WalkScientists have used a wireless “brain-spinal interface” to bypass spinal cord injuries in a pair of rhesus macaques, restoring intentional walking movement to a temporarily paralyzed leg.

Herbal Medicine May Make Tuberculosis Easier To Treat

Robert Abramovitch uses a synthetic biosensor that glows green in response to conditions that mimic TB infection, something he developed earlier in his research. (Credit: Michigan State)

A centuries-old herbal medicine, discovered by Chinese scientists and used to effectively treat malaria, may help treat tuberculosis and slow the evolution of drug resistance.

How Bacteria In Your Mouth May Trigger Arthritis

How Bacteria In Your Mouth May Trigger ArthritisThe bacteria that cause chronic gum infections may also trigger the autoimmune inflammation in rheumatoid arthritis (RA), new evidence suggests.

Why We Need A Vaccine For Periodontitis, The Gum Disease

Why We Need A Vaccine For Periodontitis, The Gum DiseaseScientists from The University of Melbourne have developed a world-first vaccine to treat gum disease. Their research, published in the journal NPJ Vaccines, has so far only tested the vaccine in mice.

How Bacteria In Undercooked Chicken Can Cause Paralysis

How Bacteria In Undercooked Chicken Can Cause ParalysisA common bacterium found in improperly cooked chicken can cause Guillain-Barré Syndrome, or GBS, the world’s leading cause of acute neuromuscular paralysis in humans.

What Makes It So Hard To Quit Drugs?

One in ten people who use alcohol or other drugs are dependent. ashey rose/Flickr, CC BY

Most people who use alcohol and other drugs do so infrequently and never become dependent (or “addicted” as it’s sometimes called). On average about 10% of people who use alcohol or other drugs are dependent.

Brain Scans Dispel Theory About Stimuli And Autism

Brain Scans Dispel Theory About Stimuli And AutismA new study challenges the hypothesis that nerve cells in the brains of people with autism spectrum disorders do not reliably and consistently respond to external stimuli.

Why Masked Hypertension Is A Silent Killer

Why Masked Hypertension Is A Silent KillerSome people with normal blood pressure have elevated blood pressure when their doctor takes the reading. This phenomenon is known as “white coat hypertension”.

Can You Sneeze Without Closing Your Eyes?

Can You Sneeze Without Closing Your Eyes?Is it possible to sneeze without closing your eyes? You might recall the age-old myth that warned against sneezing with open eyes to mitigate the possibility of eyeballs popping out. Tales swirled for decades speculating that...

Why Iron Is Such An Important Part Of Your Diet

Why Iron Is Such An Important Part Of Your DietAccording to the World Health Organization, iron deficiency – a condition where your body doesn’t have enough of the mineral iron – is a global public health problem of “epidemic proportions”.

How The Brain Changes In Alzheimer's Disease

How The Brain Changes In Alzheimer's DiseaseMost people have heard of Alzheimer’s disease, the most common form of dementia. The disease has no cure and few, but inefficient, treatments.

Smoking Harms Both Your Physical Health And Mental Health

Smoking Harms Both Your Physical Health And Mental HealthA middle-aged cigarette smoker who has smoked for decades is two to three times more likely to die early than someone similar who has never smoked.

This New Drug Helps Radiation Kill Prostate Cancer

 This New Drug Helps Radiation Kill Prostate CancerAn experimental drug appears to pack a one-two punch against some prostate cancers, significantly slowing the increase of cancer cells and making them more vulnerable to radiation.

There Is A Wrong Way To Talk About Alzheimer’s Disease

There Is A Wrong Way To Talk About Alzheimer’s DiseaseExperts suggest avoiding war metaphors, such as “attacking” beta amyloid, when talking about Alzheimer’s disease. While war comparisons can motivate efforts to deal with a health issue, this type of language and messaging can also create fear and stigma...

Why Is Glaucoma The Sneak Thief Of Sight?

Why Is Glaucoma, The Sneak Thief Of Sight?If you’re one of the millions of Australians who regularly see an optometrist, you’re probably familiar with having your eye pressure checked as part of a comprehensive eye examination.

Oxygen Therapy Doesn’t Benefit Everyone With COPD

Oxygen Therapy Doesn’t Benefit Everyone With COPDA new study indicates that supplemental oxygen does not benefit a large group of patients with COPD: those with moderately low levels of oxygen in the blood.

What to Do When a Loved One Says, "I Have Cancer"

What to Do When a Loved One Says, "I Have Cancer"More and more people must struggle with how to face the new reality of a life-threatening disease. And over on the sidelines, friends and loved ones struggle with how best to support them.

Hearing Voices Is More Common Than You Think

Hearing Voices Is More Common Than You ThinkHearing voices that other people can’t is a meaningful experience. Like dreams, they can usually be understood in terms of one’s life experiences.

What Is Carpal Tunnel Syndrome And How To Treat It?

What Is Carpal Tunnel Syndrome And How To Treat It?It often begins as an easily dismissed tingle in the thumb or an ache in the wrist. Building slowly but persistently to a searing, tearing pain from the wrist to the fingers.

What Causes Knock Knees And Do They Have To Be Treated?

Pathological knock knees Wikimedia CommonsKnock knees, also known as genu valgum, is a type of knee alignment seen when a child (or adult) stands up straight with their knees together, but their feet and ankles stay apart.

Can Drinking Coffee Reduce Your Dementia Risk?

Can Drinking Coffee Reduce Your Dementia Risk?Alzheimer’s disease, the most common form of dementia, is a growing problem worldwide. There are 350,000 people with dementia in Australia and this is set to rise to 900,000 by 2050. There is no cure for Alzheimer’s disease.

Is There A Natural Limit To How Long Humans Can Live?

Is There A Natural Limit To How Long Humans Can Live?Humans may live longer and longer, but eventually we all grow old and die. This leads to a simple question: is there an intrinsic maximum limit to human lifespan or not?

What Happens When People With Autism Grow Old?

What Happens When People With Autism Grow Old?If you mention autism to most people they will think about children, but it is a lifelong diagnosis. Children with autism grow up to be adults with autism. Little is known about how the symptoms change with age.

How Brain Training Could Add Years Behind The Wheel

How Brain Training Could Add Years Behind The WheelOlder adults who participate in training designed to improve cognitive ability are more likely to continue driving over the next 10 years than those who don’t, research shows.

What Is Conjunctivitis And How Did I Get It?

What Is Conjunctivitis And How Did I Get It?Conjunctivitis is an eye disease that has been described since antiquity. Ancient Roman oculists, the eye physicians of the time, prescribed remedies such as vinegar lotions and copper oxide for its treatment.

Can A Simple Blood Test Detect Cancer?

Can A Simple Blood Test Detect Cancer?Breast cancer could be detected using a blood test, according to reports out today. Scientists at the Australian National University (ANU) are working with counterparts in France to make this form of cancer detection, that is far less invasive and expensive than other tests such as biopsies, a reality.

What Is Spice And Why Is The Drug So Dangerous?

What Is Spice And Why Is The Drug So Dangerous?Synthetic cannabis, of which Spice is an example, is linked to serious health issues ranging from difficulties breathing to psychotic episodes.

What Are Cataracts and How Are They Treated?

What Are Cataracts and How Are They Treated?Nearly one-third of Australians aged 55 or over (or around 1.5 million people) have an untreated cataract. In 2013-14, there were 229,693 hospital admissions for cataract surgeries, making cataracts one of the most prevalent conditions among Australians.

There Is More Than One Kind Of Alzheimer’s Disease

There Is More Than One Kind Of Alzheimer’s DiseaseRelying on clinical symptoms of memory loss to diagnose Alzheimer’s disease may miss other forms of dementia caused by Alzheimer’s that don’t initially affect memory, a new study suggests.

Quitting Smoking Pays Off, Even For Those Considered High-risk

Quitting Smoking Pays Off, Even For Those Considered High-riskQuitting smoking improves health and lowers odds of developing lung cancer. And even among smokers with a genetic predisposition to smoking heavily and developing lung cancer at a young age, the benefits of quitting are significant.

What Are The Signs Of Meningococcal Meningitis?

Stories of meningococcal outbreaks tell us it’s that season again. But what is meningococcal meningitis, why does it occur in seasons, and why does it strike fear into the hearts of so many?

How To Know Whether To Forgo Chemo For Early Stage Breast Cancer

How To Know Whether To Forgo Chemo For Early Stage Breast CancerThere has been substantial publicity about the MINDACT trial, which could lead to changes in breast cancer treatment. The study’s results suggest that women with a certain genetic profile would have a good chance of survival and cure regardless of chemotherapy.

Why Singing May Help People With Dementia

Why Singing May Help People With DementiaA few years ago, I was in the audience for a live radio show, when the renowned American country singer Glen Campbell took to the stage.

Concussions In Children Have Implications Beyond What We Thought

Concussions In Children Have Implications Beyond What We ThoughtHead knocks in childhood are by no means uncommon, yet they may have lasting negative effects. New research has found a link between concussion in childhood and adverse medical and social outcomes as an adult.

4 Tips for Using Your Brain to Calm Pain

4 Tips for Using Your Brain to Calm PainAbout 100 million Americans—one in three people—suffer from ongoing pain that impacts their daily lives. Chronic pain has fueled a pain treatment crisis resulting in the overprescribing of risky opioids. The tragic deaths of celebrities such as Prince have brought the issue to public awareness in a way that statistics can't.

5 Misconceptions About Lower Back Pain

5 Misconceptions About Lower Back PainLower back pain is the greatest source of global disability, ahead of nearly 300 other conditions, leading to huge levels of healthcare costs and suffering. And the effects go far beyond pain, weakness and stiffness – they also have a huge impact the social and family lives of sufferers.

Zika Virus Echoes Of US Rubella Outbreak Of 1964-65

The Zika Virus Echoes Of US Rubella Outbreak Of 1964-65Just over 50 years ago, a highly contagious but seemingly harmless virus swept through the United States, infecting as many as 12.5 million people. In both adults and children, the virus presented as a mild illness, but caused birth defects in some babies born to women who were infected while pregnant.

Diabetes Treatment Could Be Revolutionized By Making People Cold

Diabetes Treatment Could Be Revolutionized By Making People ColdFor people in northern countries enjoying summer sun, I hate to put a dampener on things but winter’s coming. The cold months can seem to go on forever, yet scientists are uncovering a new reason to be grateful for them.

Is Addiction A Disease Or Behavioral Problem?

 If people see their addiction as a learnt behaviour, will it be easier for them to stop? f

We used to think of “addiction”, or what we now call dependence, as a moral failing. This had the result of blaming the person who was addicted – it was a matter of willpower and they just weren’t trying hard enough. So the obvious solution was shaming and scolding until they did.

The A, B, C, D And E Of Hepatitis

Hepatitis means inflammation of the liver. While we usually think of hepatitis A to E viruses, anything that causes inflammation or damage to the liver can be considered as a form of hepatitis.

Type 2 Diabetes Increasingly Affects The Young And Slim

Type 2 Diabetes Increasingly Affects The Young And SlimIt is well recognised that increasing rates of type 2 diabetes are mainly driven by obesity and lifestyle factors. But that’s not the whole story. Genetics and epigenetics – changes in gene expression – also play an important role.

Memory And Sense Of Self May Play More Of A Role In Autism

Memory And Sense Of Self May Play More Of A Role In AutismIt’s well-known that those with autism spectrum disorders including Asperger’s syndrome develop difficulties with social communication and show stereotyped patterns of behaviour.

Is Natural Selection The Answer To The Cancer Riddle?

Is Natural Selection The Answer To The Cancer Riddle?Essential organs tasked with keeping us alive and reproducing – such as the heart, brain or uterus – may have evolved better protection against cancer than larger and paired organs, we have proposed.

If I Develop Alzheimer's, Will My Children Get It Too?

If You Develop Alzheimer's, Will Your Children Get It Too?The most common question I get asked is “Will my child get Alzheimer’s disease?” In my experience, this concern is one of the biggest worries for sufferers, and given the devastating effects of the disease, it is not hard to see why it is a difficult thought to contemplate.

House Dust Reveals How Amish Kids Avoid Asthma

House Dust Reveals How Amish Kids Avoid AsthmaSpecific aspects of the Amish environment are associated with changes to immune cells that appear to protect children from developing asthma, report researchers.

The Keys to Emotional Balance based on Principles of Chinese Medicine

The Keys to Emotional Balance based on Principles of Chinese MedicineMost Eastern styles of medicine pay just as much attention to the patient’s state of mind as to the state of his or her tissues and organs. This insight and acknowledgment of the whole person rather than reducing us to our individual body parts is based on healing methods centuries old that survive because they work.

What A Hominid Fossil Can Teach Us About Cancer

Volume rendered image of the external morphology of the foot bone shows the extent of expansion of the primary bone cancer beyond the surface of the bone. Patrick Randolph-Quinney (UCLAN)In late July, an international team of researchers announced that they had identified evidence of cancer in the fossilized remains of a biological relative of human beings who lived about 1.7 million years ago.

Is A Solution To Antibiotic Resistance Right Under Our Noses?

Is A Solution To Antibiotic Resistance Right Under Our Noses?Alexander Fleming discovered penicillin in 1928 and revolutionised the treatment of bacterial infections. Ever since then we have been searching for new antibiotics to address the myriad of infections humans encounter and the growing risk of resistance to them.

Everything You Need To Know About Chickenpox

Everything You Need To Know About ChickenpoxRecent calls for the introduction of a vaccine against chickenpox (varicella-zoster virus infection) following a severe case of the disease in Cambridge, England may surprise many parents who consider the disease to be a mild illness that “everyone gets”.

Why You Could Be At Risk For Diabetes

Risk For Diabetes 8 8Type 2 diabetes has reached epidemic proportions, with an estimated 29 million people in the U.S. having the disease and another 86 million considered prediabetic. With an estimated cost of US$245 billion, prevention becomes critically important to stem the tide of increasing diabetes prevalence.

What Governments Can Do About The Mental Health Crisis

Mental Health CrisisA recent report by the Mental Health Network, found that 19% of adults had been diagnosed with depression at some point in their lives, while as many as one in four people experience a mental health problem in any given year.

Why Normal People Experience Road Rage?

Why Normal People Experience Road Rage?Anger can be very quick, powerful, reactive, and can make us do things we typically wouldn’t do. There is nothing inherently wrong with anger as an emotion, but nowhere is anger less helpful, more common, and potentially more dangerous than when we are behind the wheel of a car.

What Science Knows About The Cure For HIV

What Science Knows About The Cure For HIVAntiretroviral therapy has revolutionised the lives of people living with HIV. In many countries, the life expectancy for someone living with the virus is now almost the same as someone who isn’t infected.

Delirium May Raise Risk Of Dying In Nursing Homes

A new analysis of the medical records of more than 5.5 million older adults admitted to nursing homes between 2011 and 2014 shows that those with delirium face an increased risk of death. They’re also more likely to be readmitted to the hospital.

How To Get More Sleep While Raising Children With ADHD

How To Get More Sleep While Raising Children With ADHDRaising a child with Attention Deficit Hyperactivity Disorder (ADHD) can be difficult. Some days feel long and the respite of a peaceful night, so rejuvenating for many, may not come at all

Myths About Gout Are Hampering Its Treatment

Myths About Gout Are Hampering Its TreatmentThe prevalence of gout is increasing worldwide. It has become the most common cause of inflammatory arthritis in men, and its prevalence in postmenopausal women continues to rise. This increase is due to changes in diet and lifestyle, increased use of certain diuretics and increasing obesity.

6 Things To Consider When Looking For A Home For Dementia Care

6 Things To Consider When Looking For A Home For Dementia CareAdmitting a loved one to a nursing home is a difficult decision and is usually only arrived at once the person’s care needs cannot be met by the family and community-based services. Dementia has profound consequences for the quality of life for those with the condition, their family and friends.

London's Great Smog Offers Clues To Asthma's Cause

London's Great Smog Offers Clues To Asthma's CauseAsthma is a chronic respiratory condition with no known cure. It impacts people of all ages through episodic constrictions of the airways, which may be even worse than it sounds.

Simple Hearing Test May Predict Autism Risk

Simple Hearing Test May Predict Autism RiskScientists have identified an inner ear deficiency in children with autism that may affect their ability to recognize speech. The finding suggests that a hearing test could one day be used identify children at risk for the disorder at an early age.

Should We Be Routinely Screened For Melanoma?

Should We Be Routinely Screened For Melanoma?The United States Preventive Services Task Force has released a report saying there isn’t enough evidence to recommend that clinicians perform visual screening for melanomas for patients with no known risk for the skin cancer.

Will Kids Grow Out Of Childhood Asthma?

Will Kids Grow Out Of Childhood Asthma?When a child is diagnosed with asthma, parents usually have a number of questions. How serious is asthma? Will the child grow out of it?

Metastatic Prostate Cancer Is Up 72% In 10 Years

Metastatic Prostate Cancer Is Up 72% In 10 YearsThe number of new cases of metastatic prostate cancer climbed 72 percent from 2004 to 2013, but it’s unclear whether the rise is due to a recent trend of fewer screenings, the disease becoming more aggressive, or both.

Tapering Off Prescription Opioids: 7 Tips for Success

Tapering Off Prescription Opioids: 7 Tips for SuccessIf you take prescription opioids, you may have experienced withdrawal symptoms at some point—perhaps when you forgot to take a scheduled dose of medication. Opioid withdrawal is highly unpleasant. If you experience withdrawal symptoms, this does not meant that you cannot get off opioids...

What's Behind The Global Rise In Short-sightedness?

What's Behind The Global Rise In Short-sightedness?Over the last century, myopia (short-sightedness) has risen to epidemic proportions. In South-East Asia nearly 90% of school leavers are now affected. In the West the figures are not as dramatic, but it appears to be similarly increasing.

Are Type 2 Diabetes And Obesity Inherited?

Are Type 2 Diabetes And Obesity Inherited?The most exciting recent development in human genetics research has been the ability to perform large-scale systematic studies of genetic variation in thousands of people.

Alzheimer's Breakthrough? Have We Nearly Cured Dementia?

Alzheimer's Breakthrough? Have We Nearly Cured Dementia?My mother-in-law called me yesterday. She doesn’t quite know what I do for a job but has a vague idea I work with a group seeking to understand and ultimately prevent Alzheimer’s disease.

Can Screwy Gut Bacteria Raise Your Diabetes Risk?

Can Screwy Gut Bacteria Raise Your Diabetes Risk?Being overweight and not getting enough exercise are considered major contributors to insulin resistance and, ultimately, type 2 diabetes. But new research suggests specific imbalances in gut bacteria play a role, too

Is It Ethical To Purchase Human Organs?

Is It Ethical To Purchase Human Organs?Organ transplantation saves lives. People with end-stage kidney disease who receive a transplant tend to live much longer than those who undergo dialysis. A kidney from a living donor will last from 12 to 20 years, on average, compared to eight to 12 years for a kidney from a deceased donor.

Know The Signs For Concussions And Kids

Know The Signs For Concussions And KidsHead trauma is a major public health concern in the United States, with indirect and direct health-care costs approaching nearly US$1 billion annually. Worse, head trauma also can cause short- and long-term health problems and, in children, problems with academics, headaches and behavioral health issues.

Should You Worry Early Onset Alzheimer's?

Should You Worry Early Onset Alzheimer's?You have forgotten where you put your car keys, or you can’t seem to remember the name of your colleague you saw in the grocery store the other day. You fear the worst, that maybe these are signs of Alzheimer’s disease.

How Brain Implants Can Let Paralyzed People Move Again

How Brain Implants Can Let Paralyzed People Move AgainSomething as simple as picking up a cup of tea requires an awful lot of action from your body. Your arm muscles fire to move your arm towards the cup. Your finger muscles fire to open your hand then bend your fingers around the handle.

Signs Of Chronic Fatigue Found In Gut Bacteria

Signs Of Chronic Fatigue Found In Gut BacteriaChronic fatigue syndrome, a condition where normal exertion leads to debilitating fatigue that isn’t alleviated by rest, has long mystified scientists. There are no known triggers, and diagnosis requires lengthy tests.

Sex And Other Myths About Weight Loss

Sex And Other Myths About Weight LossThe estimated annual health care costs related to obesity are over $210 billion, or nearly 21 percent of annual medical spending in the United States.

Why Lyme Disease Is Such A Danger

Hitting the target. Hannah Garrison/wikimedia, CC BY-SAOn any ranked list of nasty diseases transmitted by mosquitoes, ticks and fleas in the Western world, Borrelia burgdorferi, would have to lie near the top. These bacteria cause Lyme disease, which was first recognised in the US in the early 1970s among patients in Lyme, Connecticut.

If Only Your Body Could Speak to Your Mind

ralph nader 6 25For thousands of years humans have defended themselves from harm by others. But many have proceeded to regularly harm themselves. They have actively searched for substances to ingest, inhale, inject and apply which may give them some immediate relief but damage or destroy their lives over time.

What Is The Common Cold And How Do We Get It?

What Is The Common Cold And How Do We Get It?The “common cold” is common. Most of us will have at least one or two per year. Children get sick more often and very young children often get more than five colds per year.

Anxiety Opens The Door To Diabetes

Anxiety Opens The Door To DiabetesScientists have uncovered a link between emotional stress and diabetes, with roots in the brain’s ability to control anxiety.

What Is Chronic Pain And Why Is It Hard To Treat?

What Is Chronic Pain And Why Is It Hard To Treat?A recent study by the National Institutes of Health found that more than one in three people in the United States have experienced pain of some sort in the previous three months. Of these, approximately 50 million suffer from chronic or severe pain.

How The British Defeated Napoleon With Citrus Fruit

Blockade of Toulon by Thomas Luny. Wikimedia CommonsEveryone knows that Britain’s conclusive victory over Napoleon was at Waterloo. The story of that day – the squares of infantry repulsing cavalry charges, the Imperial Guard retreating under murderous musket fire delivered by a red line of soliders, the just-in-time arrival of Field Marshal Blücher’s Prussian army – is one of excitement, horror and heroism.

To Fight Zika, Let's Genetically Modify Mosquitoes The Old-fashioned Way

Researchers are working out mass rearing techniques for Aedes mosquitoes – their generation time is only 2.5 weeks. IAEA Imagebank, CC BY-NC-NDThe near panic caused by the rapid spread of the Zika virus has brought new urgency to the question of how best to control mosquitoes that transmit human diseases. Aedes aegypti mosquitoes bite people across the globe, spreading three viral diseases: dengue, chikungunya and Zika.

Blame Your Immune System If You Are Mysteriously Itchy

Blame Your Immune System If You Are Mysteriously Itchy"As doctors, we throw things like antihistamines, ointments, and lotions at patients who suffer chronic itching, but if there is something profoundly abnormal about the immune system—as it appears there is—then we can't solve the itching until we address those underlying causes," says Brian S. Kim.

Why The Approach To Tackle This Silent Killer Has Changed

Why The Approach To Tackle This Silent Killer Has ChangedTraditionally, someone who suffered from hypertension – or high blood pressure – would only receive treatment when his or her blood pressure was measured and the reading was found be higher than normal. But this meant that the condition was often picked up only when the person had a stroke or a heart attack – and in many instances this was too late.

Your Risk Of Dying Hinges On Well-being Not Diseases

Your Risk Of Dying Hinges On Well-being Not Diseases"A shift of attention is needed from disease-focused management, such as medications for hypertension or high cholesterol, to overall well-being across many areas," says William Dale.

Is Addiction A Brain Disease?

Is Addiction A Brain Disease?The opioid abuse epidemic is a full-fledged item in the 2016 campaign, and with it questions about how to combat the problem and treat people who are addicted.

Are Older Adults More Prone To Chronic Pain?

Are Older Adults More Prone To Chronic Pain?"If older adults are more likely to have these pain messages sent through the spinal cord to the brain, and the nervous system is being adapted to go through these changes, they may become more pain prone," says Joseph Riley.

Has Canada Turned The Corner On Childhood Obesity?

Has Canada Turned The Corner On Childhood Obesity?Children in Canada, their parents, health professionals and government ministers will welcome the news that there has been a decline in overweight and obese children over the past ten years. The reduction in the proportion of children in Canada who are overweight or obese is a rare achievement.

What Are Delusions And How Best Can We Treat Them?

What Are Delusions And How Best Can We Treat Them?From believing that clouds are alien spaceships to thinking that MI6 agents are following you in unmarked cars, delusions are the hallmark of severe mental illness.

Why Men Don't Like To Talk About Their Enlarged Prostate

Why Men Don't Like To Talk About Their Enlarged ProstateConversation about how often you have to get up at night for a piddle is probably not the most scintillating discourse. But there’s a much bigger reason men don’t like to talk about prostate conditions.

Breast Cancer Seems A Woman's Disease, But Men Get It Too

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University of Copenhagen rightOriginal Study

Posted by on January 27, 2015

Three of the four most fatal cancers are caused by the protein “Ras”—because it mutates or simply because it ends up in the wrong place at the wrong time.

Ras has proven an elusive target for scientist trying to cure the deadly diseases. Now chemists at the University of Copenhagen has discovered an unknown way for Ras to find its proper place in the cell. Their discovery may lead to completely novel approaches to curing cancer.

Ras proteins inhabit the interior wall of each and every cell in the human body. Their role is to activate cell division or cell growth, so cancers develop if the protein starts to permanently trigger cells to grow and split: a process known as misregulation.

Ras misregulates if it misses its correct location on the cell wall: its membrane.

What the scientists discovered is that Ras cannot reach its designated location if the membrane has the wrong shape, explains Professor Dimitrios Stamou.

“If the curvature of the cell is right, Ras goes to the right place. If the membrane is too straight or too bent, it does not. And Ras is very much like any other worker. If it never finds the way to its workplace, it is not likely to get any work done,” says Stamou.

Lethal lung, colon, and pancreas cancers

Ras proteins are thought to be misregulated in upwards of 30 percent of all cancers, and are specifically linked to highly lethal strains in lungs, colon, and pancreas.

For three decades researchers have been searching for ways to squelch the killer protein. Their lack of success has given Ras a reputation as the “undruggable cancer target.”

Stamou’s research is moving in an entirely new direction.

“If Ras goes off the rails because of changes in the curvature of the cell, perhaps we should target whatever changes the shape of the cell membrane,” says Stamou. “This is a change of perspective similar to when we went from flying with hot air balloons to taking off with fixed wings and propellers.”

Controversial approach?

Looking for a correlation between cell shape and Ras misregulation was unusual, even bordering on controversial, says Jannik Bruun Larsen, a postdoctoral student.

The team was investigating how the proteins attach themselves to the cell wall, and Larsen tried to attach Ras to a variety of simulated cell membranes formed into small spheres or vesicles of varying sizes.

Ras would attach more readily to smaller balls. These are more curved than large and Larsen started to see a pattern.

“For more than a decade, people thought that the constituents of the cell wall was what controlled where Ras was localized. We have shown that at least one other aspect, namely membrane curvature, governs where Ras ends up in the cell and is therefore likely to be a factor in cancer development,” says Larsen.

‘We have started’

All of the research so far has taken place on simulated systems in test tubes. The next big challenge is to uncover how these effects play out in living systems, asserts Stamou.

“It will be ten times more difficult to uncover these effects in living systems but it needs to happen. We have started, and we really hope others will follow,” says Stamou.

“It may prove complicated to develop a drug that changes the shape of cells but I am certain that the discovery of the shape/misregulation correlation will at least lead to new ways to diagnose cancers.”

The findings appear in the journal Nature Chemical Biology.

Source: University of Copenhagen

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